DiCE Molecules Careers

DiCE is committed to hiring and supporting a team of talented, creative and intelligent individuals. In addition to an exciting and rewarding start-up environment, we offer a comprehensive compensation and benefits package to all employees:

  • Competitive Base Salary
  • Stock Options
  • Medical – PPO & HMO
  • Dental
  • Vision
  • Life Insurance, Disability
  • 401(k)
  • Non-Accrual Vacation Policy
  • Work-Life Balance

Current Openings

Interested candidates may submit their resume along with a cover letter to hr@dicemolecules.com. Resumes may also be submitted without applying for a specific job.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, please contact us at 650-566-1402 for assistance.

DiCE is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status or veteran status.

Job Description:

DiCE Molecules is focused on the development of DNA-programmed chemical synthesis and its application to drug discovery.  Our innovative platform unites the power of directed evolution with organic synthesis to identify and optimize hits against challenging pharmaceutical targets.

We seek an exceptional Scientist with a strong background in organic chemistry, medicinal chemistry and/or combinatorial chemistry.  The candidate’s primary responsibilities will include development and execution of chemistry strategy for DiCE’s research programs including development of DNA-compatible synthetic chemistry, library design, and progression of emerging hits into lead optimization.  In addition to providing strong scientific leadership, the successful candidate will be responsible for organizing internal and external resources and collaborating across disciplines to ensure efficient research progress.  The preferred candidate will have a demonstrated track record of scientific success in a multidisciplinary environment.  An active laboratory program will be a key component of the role.

Key Skills Required:

  • Highest integrity; committed to ethics and scientific standards
  • Synthetic organic chemistry and analytical techniques such as HPLC and LCMS
  • Exceptional scientific thinker, ability to drive innovation and creative thinking
  • Strong organizational and time-management skills
  • Excellent written and oral communication skills
  • Strong interpersonal skills with the ability to collaborate with and influence others at all levels
  • Team player; comfortable and effective in a collaborative research environment
  • Commitment to ensuring laboratory safety

Education and Experience:

A PhD in organic chemistry with 0-4 years of industry experience is preferred.

Apply Now

Job Description:

DiCE Molecules is focused on the development of DNA-programmed chemical synthesis and its application to drug discovery.  Our innovative platform unites the power of directed evolution with organic synthesis to identify and optimize hits against challenging pharmaceutical targets.

We seek an exceptional Research Associate or Senior Research Associate with a strong background in Organic Chemistry, Combinatorial Chemistry and/or Medicinal Chemistry.  The candidate’s primary responsibilities will include the development, synthesis, execution and analysis of combinatorial DNA-programmed libraries. The candidate will also be responsible for developing and executing “off-DNA” syntheses via standard organic synthetic methods and solid-phase synthesis.  We offer a stimulating, challenging and productive research environment with a strong commitment to developing the chemistry skills of our people.

Key Skills Required:

  • Highest integrity; committed to ethics and scientific standards
  • Synthetic organic chemistry
  • Analytical techniques such as HPLC and LCMS
  • Purification of final compounds
  • Thorough scientific record keeping
  • Strong organizational and time-management skills
  • Excellent written and oral communication skills
  • Team player; comfortable and effective in a collaborative research environment
  • Relevant computer software including Excel & chemical drawing; experience with electronic notebooks preferred
  • Commitment to ensuring laboratory safety

Education and Experience:

A BS or MS degree in chemistry or organic chemistry with at least 2 years of industry experience is preferred.  Exceptional candidates with fewer years of industrial experience will be considered.

Apply Now

Job Description:

DiCE Molecules is focused on the development of DNA-programmed chemical synthesis and its application to drug discovery. Our innovative platform unites the power of directed evolution with organic synthesis to identify and optimize hits against challenging pharmaceutical targets. We are a startup with ~ 25 employees located in Redwood City, California. Join our team and take part in transforming traditional Medicinal Chemistry by performing optimization on a massive scale.

We seek an exceptional chemoinformatics scientist to join our Informatics team. Responsibilities include building and utilizing tools to analyze results from DNA-programmed libraries of small molecules to prioritize “hits” for resynthesis as well as identifying commercially available building blocks to develop structure activity relationships. The candidate will work closely with the chemistry team during the library design, synthesis, and hit profiling stages on multiple targets and libraries.

Candidate must (i) have a firm understanding of the medicinal chemistry process and drug property design (ii) be comfortable manipulating and drawing conclusions from large datasets, taking many factors and types of data into consideration and (iii) have familiarity and skills in chemoinformatics including physicochemical property prediction, library enumeration, chemical fingerprinting, and substructure searching. Familiarity with tools such as Pipeline Pilot, Vortex/Spotfire, Knime, R, Python, and experience with chemical registration databases (e.g. Dotmatics) is preferred.

Key Skills Required:

  • Highest integrity; committed to ethics and scientific standards
  • Experience in drug design and optimization
  • Experience with chemoinformatics
  • Exceptional scientific thinker, ability to drive innovation and creative thinking
  • Strong organizational and time-management skills
  • Excellent written and oral communication skills
  • Strong interpersonal skills with the ability to collaborate with and influence others at all levels
  • Team player; comfortable and effective in a collaborative research environment

Education and Experience:

PhD in chemistry, computational chemistry, or chemoinformatics or MS/BS in chemistry with 4-8 years laboratory experience in Medicinal Chemistry.

 

Apply Now

Notice To Search Firms/Third Party Recruitment Agencies (Recruiters)

The Human Resources team manages the recruitment and employment process for DiCE Molecules. Unsolicited resumes sent to DiCE from recruiters do not constitute any type of relationship between the recruiter and DiCE and do not obligate DiCE to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring managers or employees.