DiCE is committed to hiring and supporting a team of talented, creative and intelligent individuals. In addition to an exciting and rewarding start-up environment, we offer a comprehensive compensation and benefits package to all employees:
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DiCE Molecules is focused on the development of DNA-programmed chemical synthesis and its application to drug discovery. Our innovative platform unites the power of directed evolution with organic synthesis to identify and optimize hits against challenging pharmaceutical targets. We are a startup with ~ 25 employees located in Redwood City, California. Join our team and take part in transforming traditional Medicinal Chemistry by performing optimization on a massive scale.
We seek an exceptional chemoinformatics scientist to join our Informatics team. Responsibilities include building and utilizing tools to analyze results from DNA-programmed libraries of small molecules to prioritize “hits” for resynthesis as well as identifying commercially available building blocks to develop structure activity relationships. The candidate will work closely with the chemistry team during the library design, synthesis, and hit profiling stages on multiple targets and libraries.
Candidate must (i) have a firm understanding of the medicinal chemistry process and drug property design (ii) be comfortable manipulating and drawing conclusions from large datasets, taking many factors and types of data into consideration and (iii) have familiarity and skills in chemoinformatics including physicochemical property prediction, library enumeration, chemical fingerprinting, and substructure searching. Familiarity with tools such as Pipeline Pilot, Vortex/Spotfire, Knime, R, Python, and experience with chemical registration databases (e.g. Dotmatics) is preferred.
Key Skills Required:
Education and Experience:
PhD in chemistry, computational chemistry, or chemoinformatics or MS/BS in chemistry with 4-8 years laboratory experience in Medicinal Chemistry.
The Human Resources team manages the recruitment and employment process for DiCE Molecules. Unsolicited resumes sent to DiCE from recruiters do not constitute any type of relationship between the recruiter and DiCE and do not obligate DiCE to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring managers or employees.