Dr. Jacobsen joined DiCE Molecules in November 2015 as vice president of chemistry where he is responsible for the design, development and execution of on-DNA chemistry to build and evaluate chemical libraries. Prior to DiCE Molecules, Dr. Jacobsen was at Theravance Biopharma (formerly Theravance, Inc.) for 18 years, most recently serving as senior director of medicinal chemistry. At Theravance, Dr. Jacobsen led three research programs in respiratory disease and helped transition six compounds into early development. As a member of the Theravance-GlaxoSmithKline Joint Project Committee (JPC), he helped advance collaboration assets through clinical trials to FDA approvals of Breo® and Anoro®. Within the medicinal chemistry department, he had line-management responsibility for as many as three medicinal chemistry teams, as well as the high-throughput purification group.
Dr. Jacobsen holds an A.B. in Chemistry from Harvard College and a Ph.D. in Organic Chemistry from the University of California, Berkeley.